Welcome to the 14th edition of RECOMB-Genetics
The 14th RECOMB-Genetics conference is co-located with RECOMB 2026 in Thessaloniki, Greece.
Organizers
| Francesco Paolo Casale | Helmholtz Munich |
| Maria Chikina | University of Pittsburgh |
| Sriram Sankararaman | University of California, Los Angeles |
| Na Cai | ETH Zürich |
Program
| Time | Session |
|---|---|
| 08:30 – 09:25 | Registration |
| 09:25 – 09:30 | Welcome (5 min) |
| 09:30 – 10:30 | Keynote 1 — Kaur Alasoo Associate Professor, Institute of Computer Science, University of Tartu Title: From GWAS to function: bridging the colocalisation gap |
| 10:30 – 10:55 | Comprehensive gene heritability estimation reveals the genetic architecture of rare coding variants underlying complex traits Zhengtong Liu, Boyang Fu, Moonseong Jeong, Prateek Anand, Aakarsh Anand, Seon-Kyeong Jang, Aditya Gorla, Jiazheng Zhu, Paivi Pajukanta, Pier Palamara, Noah Zaitlen, Richard Border and Sriram Sankararaman |
| 11:00 – 11:40 | Coffee break |
| 11:40 – 12:05 | Resolving Variants of Uncertain Significance at Scale with Calibrated Computational and Experimental Evidence Predrag Radivojac |
| 12:05 – 12:30 | Gene-based calibration of high-throughput functional assays for clinical variant classification Daniel Zeiberg, Ross Stewart, Shantanu Jain, Malvika Tejura, Abbye McEwen, Shawn Fayer, Yuriy Sverchkov, Mark Craven, Vikas Pejaver, Alan Rubin, Lea Starita, Douglas Fowler, Anne O’Donnell-Luria and Predrag Radivojac |
| 12:30 – 12:55 | Fine-Tuning Genomic Language Models for Variant Pathogenicity Prediction Yaqi Su, Yu-Jen Lin and Garv Goswami |
| 13:00 – 14:30 | Lunch break |
| 14:30 – 14:55 | Critical Assessment of Genome Interpretation (CAGI) 7 ARSA missense stability prediction challenge identifies computational advances over state-of-the-art variant impact predictors Yu-Jen Lin, Michael Gelb and Steven Brenner |
| 14:55 – 15:20 | A Replication-Testing Framework for Single-Cell Gene Regulatory Edge Rankings Yunwei Zhao, Ankit Bhardwaj and Lakshminarayanan Subramanian |
| 15:20 – 15:45 | Invited Talk — TBD |
| 15:50 – 16:30 | Coffee break |
| 16:30 – 17:30 | Keynote 2 — Jingyi Jessica Li Professor and Program Head of Biostatistics, Fred Hutch Cancer Center; Donald and Janet K. Guthrie Endowed Chair in Statistics Title: Synthetic Data as a Statistical Engine: Fast FDR Control, Population-Scale Genomics, and Privacy Preservation |
| 17:30 – 19:00 | Poster session |
Keynote Speakers
| Kaur Alasoo | Associate Professor, Institute of Computer Science, University of Tartu |
| Jingyi Jessica Li | Professor and Program Head of Biostatistics, Fred Hutch Cancer Center; Donald and Janet K. Guthrie Endowed Chair in Statistics |
Submission Link
The EasyChair link is the same as main conference, select “The 14th RECOMB Satellite on Computational Methods in Genetics” track.
https://easychair.org/my/conference?conf=recomb2026
Key Dates
- Submissions open: 1 February 2026
- Submission deadline:
13 March2 April 2026, 23:59 (AoE) - Notification of decisions: 13 April 2026, 23:59 (AoE)
- Satellite Meeting: 25 May 2026
Accepted Posters
-
Epithelial Barrier Failure as a Missing Therapeutic Target in Oral Lichen Planus: Insights from Comparative Transcriptomics
Loulwah Alothman, Mougina K Eltahir and Alaa Alnoor Alameen -
Bayesian modeling of longitudinal metatranscriptomics experiments shows shared predictive signature associated with meat spoilage at different temperatures
Elio Nushi, Julia Manninen, Per Johansson, Elina Jääskeläinen, Johanna Björkroth and Antti Honkela -
Genetic Regulation of the Placenta in Preeclampsia
Gamze Yazgeldi Gunaydin, Jaakko Leinonen, Hannele Maaret Laivuori, Juha Kere, Satu Wedenoja and Shintaro Katayama -
mitoMatch - A Machine Learning Approach to Identify Human Relatedness Using Mitochondrial DNA Hypervariable Region I and II
Saliha Ziyard, Ruvan Weerasinghe and Rupika Wijesinghe -
Multimodal integration of gene expression and alternative splicing in single-cell and spatial transcriptomics
Arsham Mikaeili Namini
Call for Papers
The 14th RECOMB Satellite on Computational Methods in Genetics will focus on current research at the intersection of genetics, computer science, statistics, and related fields in gathering and analyzing genetic and genealogical data with applications toward problems in medicine and basic research. Population genetics allows more refined understanding of the demographic history of our species, association analysis provides insights regarding the functional and molecular underpinnings of diseases and traits, while clinical applications suggest genetics as a trailblazer into personalized medicine. The complex bioinformatic questions arising range from inferring more nuanced statistical models of genetic information to algorithms that overcome the computational challenges of analyzing millions of SNPs across millions of individuals, to systems level challenges of processing and storing Big Data repositories of genotypes and phenotypes.
The satellite meeting will take place in Thessaloniki, Greece on 25 May 2026, directly preceding the main RECOMB conference.
Topics of interest (including but not limited to)
- Population genetics
- Functional genomics
- Germline and somatic variation
- Clinical genomics
- Statistical genetics
- Machine learning application in genetics
- Sequencing technologies
- Single-cell sequencing
Submissions
We solicit contributions in three categories (“tracks”):
- Proceedings track: Submissions should describe original work on computational methods in genetics. Authors of manuscripts that are selected for oral presentation at RECOMB-Genetics after review will be encouraged to host their manuscript on a public preprint server.
- Highlights Track: This track is for papers that have already been published or are in press (and linked from the journal website) within the past year. Submissions must contain a 1 page abstract submitted to EasyChair.
- Posters: Regular abstracts describing original work or published work (including work in press) can be submitted for poster presentation. Submissions must contain a 1 page abstract submitted to EasyChair.
Paper and abstract submission procedure
Manuscripts for the “proceedings track” should not exceed 10 pages using at least 11 point font on U.S. standard 8 1/2 by 11 inch paper with no less than one inch margin all around. This excludes the cover page and references. The cover page should have the title and the corresponding author’s email address. An optional short appendix, if absolutely necessary, can be included but will be considered at the discretion of the program committee. Manuscripts must be submitted electronically in PDF format via the EasyChair system.
Authors will be notified of acceptance or rejection by email on or before 13 April 2026. An author of each accepted paper is expected to attend the workshop (if held in person) and present the paper; otherwise, alternative arrangements should be made to have the paper presented.
Special handling of papers submitted to RECOMB 2026
If you would like to consider submitting a paper rejected by RECOMB 2026 to the workshop, you may do so by the regular deadline of 13 March 2 April 2026. You must include in your submission a cover letter that includes the reviews received from RECOMB together with a rebuttal addressing the concerns raised by the reviewers. The submitted manuscript should also be modified according to the reviews, or provide an explanation of why modifications are unnecessary. All reviews will be treated confidentially and will only be visible to the PC members.
The submission system will be open starting 1 February 2026 and ending 13 March 2 April 2026. The Program Committee will referee the conference submissions.