RECOMB-CCB 2019

Registration

Opening and Welcome Remarks

Keynote

Decoding Epigenetic States of Immune and Cacncer Cells

Christina Leslie

1:10 PM - 2:10 PM

Cancer Evolution

Chair: Layla Oesper

Distance Measures for Tumor Evolutionary Trees

Summarizing the Solution Space in Tumor Phylogeny Inference by Multiple Consensus Trees [Late Breaking Research]

Minimal functional driver gene heterogeneity among untreated metastases [Highlight]

Identifying Drug Sensitivity Subnetworks with NETPHLIX [Late Breaking Research]

Coffee Break

Transcriptomics I

Chair: Yoo-Ah Kim

Chromatin-informed inference of transcriptional programs in gynecologic and basal breast cancers [Late Breaking Research]

Deep Genomic Signature for early metastasis prediction in prostate cancer

Poster Session

5:00 PM - 6:00 PM

Venue: Marvin Center, Room 309

Keynote

Pathomics, Tumor Infiltrating Lymphocytes, Clinical Studies and Cancer Surveillance

Joel Saltz

8:50 AM - 9:50 AM

Transcriptomics II

Chair: Yoo-Ah Kim

Integrated Transcriptomic-Genomic tool Texomer profiles cancer tissues [Highlight]

Uncovering and characterizing splice variants associated with survival in lung cancer patients

Coffee Break

Pathways

Chair: Ben Raphael

Uncovering the subtype-specific temporal order of cancer pathway dysregulation

An Estrogen Regulated Feedback Loop Limits the Efficacy of Estrogen Receptor Targeted Breast Cancer Therapy [Highlight]

Modeling Clinical and Molecular Covariates of Mutational Process Activity in Cancer [Late Breaking Research]

Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures [Highlight]

Lunch Break

Keynote

Eytan Ruppin

1:50 PM - 2:50 PM

Proteomics

Chair: Max Leiserson

Aberrant ERBB4-SRC Signaling as a Hallmark of Group 4 Medulloblastoma Revealed by Integrative Phosphoproteomic Profiling [Highlight]

High-throughput binding prediction of Class I and Class II neoantigens with MHCnuggets [Late Breaking Research]

Coffee Break

Single Cell

Chairs: Rachel Karchin

SCMarker: ab initio marker selection for single cell transcriptome profiling

Inference of single-cell genotypes characterizes the genetic heterogeneity in pancreatic cancer precursor lesions [Highlight]

Single-cell phylogenetic inference with copy-number supported mutation losses [Late Breaking Research]

SCIFIL: analysis of evolutionary history and clonal selection in cancer populations using single-cell sequencing data

Closing Remarks

Reception

6:00 PM - 8:00 PM

Venue: Marvin Center, Room 309