{"id":2425,"date":"2022-01-14T23:08:24","date_gmt":"2022-01-14T23:08:24","guid":{"rendered":"https:\/\/recomb2022.net\/?page_id=2425"},"modified":"2022-05-22T22:05:02","modified_gmt":"2022-05-23T05:05:02","slug":"recomb-ccb","status":"publish","type":"page","link":"https:\/\/recomb2022.net\/recomb-ccb\/","title":{"rendered":"RECOMB-CCB"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"2425\" class=\"elementor elementor-2425\">\n\t\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-40ee78c elementor-section-height-min-height elementor-section-boxed elementor-section-height-default elementor-section-items-middle\" data-id=\"40ee78c\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-ebb40e4\" data-id=\"ebb40e4\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-a77a241 elementor-widget elementor-widget-text-editor\" data-id=\"a77a241\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.7.2 - 21-08-2022 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#818a91;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#818a91;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<h3><span style=\"color: rgb(255, 255, 255); font-size: 2.11765rem; font-style: inherit;\"><br><\/span><\/h3><h3><span style=\"color: rgb(255, 255, 255); font-size: 2.11765rem; font-style: inherit;\">RECOMB-CCB 2022<\/span><br><\/h3>\n<h3><span style=\"color: #ffffff;\">The RECOMB Satellite Workshop on&nbsp;Computational Cancer Biology 2022<\/span><\/h3>\n<h4><span style=\"color: #ffffff;\">La Jolla, USA, May 20 &#8211; 21, 2022<\/span><\/h4>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-7456d48 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"7456d48\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-86688fd\" data-id=\"86688fd\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4c39983 elementor-widget elementor-widget-text-editor\" data-id=\"4c39983\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h3 style=\"font-size: 2.11765rem; font-style: normal;\">RECOMB-CCB 2022<\/h3><p style=\"font-size: 17px; font-style: normal; font-weight: 400;\"><span style=\"font-style: inherit; font-weight: inherit; background-color: var(--ast-global-color-4); color: var(--ast-global-color-3);\">This workshop brings together leading researchers in the mathematical, computational, and life sciences to discuss emerging frontiers in computational cancer research. Advent of exciting technologies such as single-cell multi-omics,\u00a0 spatial sequencing, and digital pathology opens new horizons for the analysis of tumor tissues. New analysis tools reveal novel aspects of cancer complexity, including the tumor mutational and phenotypic landscape, evolutionary history, or interactions with the microenvironment. The emphasis of all contributed work will be on applying algorithmic, mathematical, and statistical approaches to improve our understanding of cancer and on the development of useful, effective, and efficient new methods in this area.<\/span><\/p><h4 style=\"font-size: 1.47059rem; font-style: normal;\">Schedule<\/h4><div><ul><li>Talks are in the Calit2 Auditorium <span style=\"color: #0000ff;\"><a style=\"color: #0000ff;\" href=\"\/satellites-directions-parking\"><b><u>(Directions)<\/u><\/b><\/a><\/span><\/li><li>The\u00a0<span style=\"color: #0000ff;\"><a style=\"color: #0000ff;\" href=\"\/satellites\/recomb-ccb-seq-scientific-communication\/\" target=\"_blank\" rel=\"noopener\"><b><u>Scientific Communication<\/u><\/b><\/a><\/span>\u00a0joint workshop with RECOMB-Seq on Saturday is also in Calit2 Auditorium<\/li><li>Registration, coffee breaks, and posters are in the Calit2 Lobby<\/li><li><span style=\"color: #0000ff;\"><a style=\"color: #0000ff;\" href=\"\/restaurants\"><u><b>Lunch on your own:<\/b><\/u><\/a><\/span> Price Center Food Court or Restaurants at Sixth College<\/li><\/ul><\/div>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3c119be elementor-widget elementor-widget-image\" data-id=\"3c119be\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.7.2 - 21-08-2022 *\/\n.elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=\".svg\"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block}<\/style>\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"2048\" height=\"922\" src=\"https:\/\/i0.wp.com\/recomb2022.net\/wp-content\/uploads\/2022\/05\/Screenshot-2022-05-15-at-14.49.48.png?fit=2048%2C922&amp;ssl=1\" class=\"attachment-2048x2048 size-2048x2048\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/i0.wp.com\/recomb2022.net\/wp-content\/uploads\/2022\/05\/Screenshot-2022-05-15-at-14.49.48.png?w=2762&amp;ssl=1 2762w, https:\/\/i0.wp.com\/recomb2022.net\/wp-content\/uploads\/2022\/05\/Screenshot-2022-05-15-at-14.49.48.png?resize=300%2C135&amp;ssl=1 300w, https:\/\/i0.wp.com\/recomb2022.net\/wp-content\/uploads\/2022\/05\/Screenshot-2022-05-15-at-14.49.48.png?resize=1024%2C461&amp;ssl=1 1024w, https:\/\/i0.wp.com\/recomb2022.net\/wp-content\/uploads\/2022\/05\/Screenshot-2022-05-15-at-14.49.48.png?resize=768%2C346&amp;ssl=1 768w, https:\/\/i0.wp.com\/recomb2022.net\/wp-content\/uploads\/2022\/05\/Screenshot-2022-05-15-at-14.49.48.png?resize=1536%2C692&amp;ssl=1 1536w, https:\/\/i0.wp.com\/recomb2022.net\/wp-content\/uploads\/2022\/05\/Screenshot-2022-05-15-at-14.49.48.png?resize=2048%2C922&amp;ssl=1 2048w, https:\/\/i0.wp.com\/recomb2022.net\/wp-content\/uploads\/2022\/05\/Screenshot-2022-05-15-at-14.49.48.png?resize=600%2C270&amp;ssl=1 600w\" sizes=\"(max-width: 1000px) 100vw, 1000px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-644f356 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"644f356\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-18a5c8a\" data-id=\"18a5c8a\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-24af3c8 elementor-widget elementor-widget-text-editor\" data-id=\"24af3c8\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h3><a style=\"font-style: inherit; font-weight: inherit; font-size: 1.47059rem;\" href=\"https:\/\/recomb2022.net\/recomb-ccb\/recomb-ccb-call-for-submissions\/\">Contributions<\/a><\/h3>\n<p><span style=\"font-style: inherit; font-weight: inherit; background-color: var(--ast-global-color-4); color: var(--ast-global-color-3);\">RECOMB-CCB 2022 invites contributions in all areas of computational cancer biology in the following formats. Details are&nbsp;<\/span><a href=\"https:\/\/recomb2022.net\/recomb-ccb\/recomb-ccb-call-for-submissions\/\">here<\/a><span style=\"font-style: inherit; font-weight: inherit; background-color: var(--ast-global-color-4); color: var(--ast-global-color-3);\">.<\/span><\/p>\n<ul>\n<li><span style=\"font-style: inherit; background-color: var(--ast-global-color-4); color: var(--ast-global-color-3);\"><b>Full papers<\/b><\/span><span style=\"font-style: inherit; font-weight: inherit; background-color: var(--ast-global-color-4); color: var(--ast-global-color-3);\"> reporting on original research (considered for publication in PLOS Computational Biology) for the <\/span><span style=\"font-weight: inherit; background-color: var(--ast-global-color-4); color: var(--ast-global-color-3);\"><i>Paper<\/i><\/span><span style=\"font-style: inherit; font-weight: inherit; background-color: var(--ast-global-color-4); color: var(--ast-global-color-3);\"> track (deadline: February 28, 2022).<\/span><\/li>\n<li><b>Abstracts<\/b> on unpublished research for the <i>Late Breaking Research<\/i> track (deadline: March 4, 2022).<\/li>\n<li><b>Highlights<\/b> of recently published (since Jan 1, 2021) high-impact research for the <i>Highlights<\/i> track (deadline: March 4, 2022).<\/li>\n<li><b>Posters<\/b> describing unpublished or recently-published work for <i>Posters<\/i> track (deadline: March 4, 2022).<\/li>\n<\/ul>\n<div>\n<div>\n<div>\n<div>\n<div>\n<h4>&nbsp;Program Committee<\/h4>\n<div>\n<ul>\n<li style=\"font-size: 17px; font-style: normal; font-weight: 400;\">Hannah Carter,&nbsp;UC San Diego (*Chair)<\/li>\n<li style=\"font-size: 17px; font-style: normal; font-weight: 400;\">Simone Zaccaria,&nbsp;University College London (*Chair)<\/li>\n<li>Andrew Mcpherson,&nbsp;Memorial Sloan Kettering Cancer Center<\/li>\n<li style=\"font-size: 17px; font-style: normal; font-weight: 400;\">Ben Raphael, Princeton University (*Steering Committee Chair)<\/li>\n<li>Cenk Sahinalp, NCI, NIH<\/li>\n<li>Ewa Szczurek,&nbsp;University of Warsaw<\/li>\n<li>Fabio Vandin,&nbsp;University of Padova<\/li>\n<li>Gryte Satas,&nbsp;Memorial Sloan Kettering Cancer Center<\/li>\n<li>Gunnar W. Klau,&nbsp;Heinrich Heine University D\u00fcsseldorf<\/li>\n<li>Jian Ma,&nbsp;Carnegie Mellon University<\/li>\n<li>Matthew Reyna,&nbsp;Emory University<\/li>\n<li>Mohammed El-Kebir,&nbsp;University of Illinois at Urbana-Champaign<\/li>\n<li>Niko Beerenwinkel,&nbsp;ETH Zurich<\/li>\n<li>Russell Schwartz,&nbsp;Carnegie Mellon University<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-066f5ef\" data-id=\"066f5ef\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8b6ce0c elementor-widget elementor-widget-text-editor\" data-id=\"8b6ce0c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div><h4 style=\"font-size: 1.47059rem; font-style: normal;\">Contacts<\/h4><\/div><div><p>Please direct your queries and comments to <a href=\"mailto:recombccb2022@gmail.com\">recombccb2022@gmail .com<\/a><\/p><\/div>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-de7ca23 elementor-shape-rounded elementor-grid-0 e-grid-align-center elementor-widget elementor-widget-social-icons\" data-id=\"de7ca23\" data-element_type=\"widget\" data-widget_type=\"social-icons.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.7.2 - 21-08-2022 *\/\n.elementor-widget-social-icons.elementor-grid-0 .elementor-widget-container,.elementor-widget-social-icons.elementor-grid-mobile-0 .elementor-widget-container,.elementor-widget-social-icons.elementor-grid-tablet-0 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.elementor-icon.elementor-social-icon{border-radius:10%}.elementor-shape-circle .elementor-icon.elementor-social-icon{border-radius:50%}<\/style>\t\t<div class=\"elementor-social-icons-wrapper elementor-grid\">\n\t\t\t\t\t\t\t<span class=\"elementor-grid-item\">\n\t\t\t\t\t<a class=\"elementor-icon elementor-social-icon elementor-social-icon-twitter elementor-repeater-item-bb18e51\" href=\"https:\/\/twitter.com\/2022Ccb\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-screen-only\">Twitter<\/span>\n\t\t\t\t\t\t<i class=\"fab fa-twitter\"><\/i>\t\t\t\t\t<\/a>\n\t\t\t\t<\/span>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3785a35 elementor-widget elementor-widget-html\" data-id=\"3785a35\" data-element_type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<a class=\"twitter-timeline\" data-width=\"100%\" data-height=\"600\" data-theme=\"dark\" href=\"https:\/\/twitter.com\/2022Ccb?ref_src=twsrc%5Etfw\">Tweets by 2022Ccb<\/a> <script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-2c76e8c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"2c76e8c\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-619273c\" data-id=\"619273c\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7a0c020 elementor-widget elementor-widget-heading\" data-id=\"7a0c020\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.7.2 - 21-08-2022 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><h3 class=\"elementor-heading-title elementor-size-default\">Keynote Speakers<\/h4><\/h3>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-4208622 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"4208622\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-9337ed8\" data-id=\"9337ed8\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-a7dae6f elementor-widget elementor-widget-heading\" data-id=\"a7dae6f\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">Nicholas McGranahan<\/h5>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a61ecb5 elementor-widget elementor-widget-image\" data-id=\"a61ecb5\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img src=\"https:\/\/i0.wp.com\/www.ucl.ac.uk\/cancer\/sites\/cancer\/files\/styles\/small_image\/public\/nicky-mcgranahan.jpg?ssl=1\" title=\"\" alt=\"Dr Nicholas McGranahan\" data-recalc-dims=\"1\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-9cc5f89\" data-id=\"9cc5f89\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f2fb1b1 elementor-widget elementor-widget-heading\" data-id=\"f2fb1b1\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">EMBO Young Investigator Lecture <\/h4>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2c1e2ad elementor-widget elementor-widget-image\" data-id=\"2c1e2ad\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img src=\"https:\/\/www.embo.org\/wp-content\/uploads\/2020\/08\/Logo.svg\" title=\"\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4082708 elementor-widget elementor-widget-text-editor\" data-id=\"4082708\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Dr Nicholas McGranahan is the group leader Cancer Genome Evolution Research Group at the University College London Cancer Institute and he is one of the leading reacher of the\u00a0TRACERx (TRAcking Cancer Evolution through therapy (Rx)) lung study, guided by the\u00a0CRUK Lung Cancer Centre of Excellence with Professor Charles Swanton and Professor Caroline Dive.\u00a0Nicholas&#8217;s lab utilizes state-of-the-art bioinformatics and evolutionary methods to decipher cancer genome evolution and to explore patterns of tumour growth and development across cancers, focussing on lung cancer. Ultimately, his lab aims to gain a deeper understanding of the rules that govern tumour evolution and anti-tumour immunity to improve patient treatment.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-523bf9c elementor-widget elementor-widget-spacer\" data-id=\"523bf9c\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.7.2 - 21-08-2022 *\/\n.elementor-column .elementor-spacer-inner{height:var(--spacer-size)}.e-container{--container-widget-width:100%}.e-container>.elementor-widget-spacer{width:var(--container-widget-width,var(--spacer-size));-ms-flex-item-align:stretch;align-self:stretch;-ms-flex-negative:0;flex-shrink:0}.e-container>.elementor-widget-spacer>.elementor-widget-container,.e-container>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer{height:100%}.e-container>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner{height:var(--container-widget-height,var(--spacer-size))}<\/style>\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-5e0764a elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"5e0764a\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-ccbc39f\" data-id=\"ccbc39f\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-414cd9b elementor-widget elementor-widget-heading\" data-id=\"414cd9b\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">Ludmil B. Alexandrov<\/h5>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-47a559e elementor-widget elementor-widget-image\" data-id=\"47a559e\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img src=\"https:\/\/i0.wp.com\/be.ucsd.edu\/sites\/be.ucsd.edu\/files\/Ludmil%20Alexandrov%5B1%5D.jpg?ssl=1\" title=\"\" alt=\"Ludmil B. Alexandrov, PhD\" data-recalc-dims=\"1\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-1fb0e72\" data-id=\"1fb0e72\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1a240a8 elementor-widget elementor-widget-text-editor\" data-id=\"1a240a8\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Ludmil B. Alexandrov is an\u00a0<span style=\"background-color: var(--ast-global-color-4);\">Assistant Professor of Cellular and Molecular Medicine\u00a0<\/span><span style=\"font-style: inherit; font-weight: inherit; color: var(--ast-global-color-3); background-color: var(--ast-global-color-4);\">and Bioengineering<\/span><span style=\"font-style: inherit; font-weight: inherit; background-color: var(--ast-global-color-4); color: var(--ast-global-color-3);\">\u00a0at UC San Diego. His research lab focuses on understanding the information hidden in large-scale omics datasets. The lab is particularly interested in elucidating the mechanisms by which cancers develop and in leveraging this knowledge for the development of better cancer prevention strategies and the improved targeting of existing cancer treatment. Throughout the past five years, the work of the lab has predominately focused on creating the concept of mutational signatures, on demonstrating the utility of mutational signatures in understanding human cancer, and on identifying mutational signatures in a plethora of diverse cancer types. Our believe is that by developing a next-generation of machine learning approaches, we can obtain a predictive-understanding of the basic molecular processes contributing to cancer develop, which will allow us to better prevent and treat human cancer.\u00a0<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-f3240c0 elementor-widget elementor-widget-spacer\" data-id=\"f3240c0\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-1468f0a elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"1468f0a\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-83da234\" data-id=\"83da234\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b9452dc elementor-widget elementor-widget-heading\" data-id=\"b9452dc\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">Oana Ursu<\/h5>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-77fee9c elementor-widget elementor-widget-image\" data-id=\"77fee9c\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"300\" height=\"300\" src=\"https:\/\/i0.wp.com\/recomb2022.net\/wp-content\/uploads\/2022\/02\/oanaursu_picture-1.jpeg?fit=300%2C300&amp;ssl=1\" class=\"attachment-medium size-medium\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/i0.wp.com\/recomb2022.net\/wp-content\/uploads\/2022\/02\/oanaursu_picture-1.jpeg?w=400&amp;ssl=1 400w, https:\/\/i0.wp.com\/recomb2022.net\/wp-content\/uploads\/2022\/02\/oanaursu_picture-1.jpeg?resize=300%2C300&amp;ssl=1 300w, https:\/\/i0.wp.com\/recomb2022.net\/wp-content\/uploads\/2022\/02\/oanaursu_picture-1.jpeg?resize=150%2C150&amp;ssl=1 150w, https:\/\/i0.wp.com\/recomb2022.net\/wp-content\/uploads\/2022\/02\/oanaursu_picture-1.jpeg?resize=100%2C100&amp;ssl=1 100w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-c63c066\" data-id=\"c63c066\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-784f6d9 elementor-widget elementor-widget-text-editor\" data-id=\"784f6d9\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Dr Oana Ursu is a postdoctoral researcher working with Dr Aviv Regev at Genentech. Oana\u2019s research is focused on learning how cells make decisions about their internal states, and how they transition between these states, using pooled high-content screens with single-cell readouts. Oana is particularly interested in cell state changes occurring as cells develop resistance to cancer therapies, and in the role of chromatin and gene regulation in allowing cells to survive different treatments. In her talk, Oana will describe efforts in collaboration with JT Neal and Jesse Boehm&#8217;s groups at the Broad Institute to study coding variants in cancer, towards mapping their roles for tumor biology and ultimately drug response. This work uses single-cell screening technologies based on Perturb-seq to distinguish between impactful coding variants with key roles in cancer and more inert passenger mutations, with a proof of concept characterization of two hundred variants in the TP53 and KRAS genes.<br><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-138454f elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"138454f\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-954df21\" data-id=\"954df21\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-b065375 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"b065375\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-e13ae1b\" data-id=\"e13ae1b\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d2f1790 elementor-widget elementor-widget-text-editor\" data-id=\"d2f1790\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-abc35d3 elementor-widget elementor-widget-text-editor\" data-id=\"abc35d3\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p style=\"text-align: center;\"><span style=\"color: #ffffff;\">Copyright \u00a9 RECOMB 2022 Organizing Committee | Theme: Astra | Image: from iStock | Website editor: Simone Zaccaria<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>RECOMB-CCB 2022 The RECOMB Satellite Workshop on&nbsp;Computational Cancer Biology 2022 La Jolla, USA, May 20 &#8211; 21, 2022 RECOMB-CCB 2022 This workshop brings together leading researchers in the mathematical, computational, and life sciences to discuss emerging frontiers in computational cancer research. Advent of exciting technologies such as single-cell multi-omics,\u00a0 spatial sequencing, and digital pathology opens &hellip;<\/p>\n<p class=\"read-more\"> <a class=\"\" href=\"https:\/\/recomb2022.net\/recomb-ccb\/\"> <span class=\"screen-reader-text\">RECOMB-CCB<\/span> Read More &raquo;<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"nf_dc_page":"","site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-global-header-display":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>RECOMB-CCB - Recomb 2022<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/recomb2022.net\/recomb-ccb\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"RECOMB-CCB - Recomb 2022\" \/>\n<meta property=\"og:description\" content=\"RECOMB-CCB 2022 The RECOMB Satellite Workshop on&nbsp;Computational Cancer Biology 2022 La Jolla, USA, May 20 &#8211; 21, 2022 RECOMB-CCB 2022 This workshop brings together leading researchers in the mathematical, computational, and life sciences to discuss emerging frontiers in computational cancer research. 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